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    Canadian pharmacies that are legit The British National Formulary currently lists rare reports of sudden hearing loss under the side effects for PDE-5 inhibitors. A full systematic review of clinical trials, observational studies and case reports is needed as is full reporting of all adverse effects to establish how common (or rare) this side effect might be. Side effects that have not been detected in randomised controlled trials, but are only detected by case reports, are often comparatively rare. This type of study, which is based on individual case reports, is important in highlighting possible adverse effects of drugs, which may not have been detected in controlled trials. They analysed individual cases to exclude other causes of hearing loss. In each case they at which drug had been used, when the user had experienced hearing loss in relation to taking the drug, and whether one or both ears were affected. 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Abalone with an estimated value of R10 000 000, en route from South Africa to China, seized at Port Elizabeth Harbour on 26 January. Methaqualone with an estimated value of R30 000 000, en route from China to South Africa, seized at OR Tambo International Airport on 31 January. Ketamine and Methaqualone (precursors to mandrax) with an estimated value of R32 000 400, en route from Kenya to South Africa, seized at OR Tambo International Airport on 10 April. Currency (ZAR & USD) valued R6 992 569, en route from South Africa to Mauritius, seized at OR Tambo International Airport on 4 May. The researchers say there is increasing evidence that PDE-5 inhibitors may induce sudden sensorineural hearing loss and that healthcare professionals in the UK need to be aware of this ‘disabling side effect’. The aim of this study was to review the current literature on the subject; to assess the number of suspected cases, and propose possible reasons for why these drugs may be having this effect. The authors of the current review note, however, that this is ‘entirely speculative’ and ‘based on assumptions about the true incidence of SSHL and PDE-5 inhibitor usage, both of which are poorly understood and recognised’. The authors contacted agencies around North and South America, Europe and Australasia for any reports of hearing loss associated with these drugs. They say that recently there have been both case reports and studies suggesting that PDE-5 inhibitor use is associated with sudden sensorineural hearing loss, a rare and emergency condition where there is damage to the inner ear structures. Erectile dysfunction is a condition that is easily self-diagnosed and suitable for self-treatment, with the support of a pharmacist,” said Mr Smith. Best place where you can buy generic erectile dysfunction drugs and medications give you the best results. 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Recent studies have shown that lowering cholesterol in people without heart disease can greatly reduce their risk for ever developing CHD, along with heart attacks and atherosclerosis. One of the effects reported recently is hearing loss, but few studies have investigated this link. 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